Alison L. Marsden
Assoc Professor, Mechanical and Aerospace Engineering
Computational fluid mechanics, cardiovascular mechanics, bio-fluid mechanics and biomedical devices technology emphasizing optimization methods relating to vascular surgery Dr. Marsden’s work explores the interface between medicine and the quantitative, physical, and theoretical disciplines. Her postdoctoral research focused on simulation and optimization of the Fontan, a surgery used to treat single-ventricle congenital heart defects. This work led to the development of a new modification of the Fontan surgery. A goal of her ongoing work is that rigorous modeling and optimization of treatments for cardiovascular disease according to engineering principles will complement doctors' clinical judgment and experience to improve outcomes for patients suffering from both congenital and acquired heart disease. In previous work, her thesis research applied novel shape optimization techniques to airfoil design for trailing-edge noise reduction in turbulent flow. This work established a viable framework for optimization in many challenging fluid mechanics problems including turbulence, complex geometries and unsteady flows. Her research interests include the development of derivative-free optimization methods, identification of vascular design principles, treatment planning for pediatric cardiology, and the development of numerical methods for fluid mechanics.
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