More than 600 people attended the UCSD Jacobs School of Engineering 24th Annual Research Expo on Friday, February 25, 2005. Follow the links in the left hand column to view the talks or slides from our plenary session on Engineering Advances in Healthcare, see the winners of our graduate student research poster contest, or view our photo gallery.

PLENARY SESSION: ENGINEERING ADVANCES IN HEALTH CARE

	Welcome, Jacobs School Highlights Frieder Seible - Dean of the Jacobs School View Slides | Watch Video, Length 15:13
	Engineering Advances in Healthcare Juan Lasheras - Prof. of Mechanical and Aerospace Engineering View Slides | Watch Video, Length 03:04
	Human Stem Cells: The Opportunities and Challenges Presented by Prop 71 Judith L. Swain, M.D., - Professor of Medicine, Stanford University; Director of the College of Integrated Life Sciences, Dean for Translational Medicine, and Professor of Medicine - Designate, UCSD View Slides | Watch Video, Length 25:29 ABSTRACT: The citizens of California have taken the unprecedented step of providing $3 billion to create the California Institute of Regenerative Medicine. This will likely establish this state as the national and international leader in human stem cell research, and in the field of regenerative medicine as a whole. Embryonic and adult stem cells biology will be discussed, including nuclear transplantation and therapeutic cloning. Some of the challenges in human stem cell research will be presented, including stem cell differentiation and the development of artificial organs ex vivo. These challenges are what will provide the opportunities for scientists and engineers. The ethical and societal issues surrounding this research will require the scientific community to actively engage the public.
	Reconstructing Genomic Architectures of Cancer Genomes Pavel Pevzner - Professor of Computer Science and Engineering View Slides | Watch Video, Length 14:22 ABSTRACT: Genome rearrangements (e.g. chromosome inversions and translocations) are commonly observed in tumor cells, and are directly implicated in the progression of some types of cancer. While many individual rearrangements in tumors have been cataloged, little is known about the detailed architecture of tumor genomes. Recently, an experimental technique called End Sequence Profiling (ESP) has produced high-resolution data about tumor genome structure. We describe the ESP Genome Reconstruction Problem whose solution reveals rearrangements in tumor genomes. We further illustrate our methods on ESP data from the MCF-7 breast tumor cell line and  derive a putative architecture of the MCF-7 genome. This is a joint work with Ben Raphael (UCSD Computer Science), and Colin Collins and Stas Volik (UCSF Cancer Center).
	Research on Medical Devices in Academe: A Tortuous Journey David Gough - Professor of Bioengineering View Slides | Watch Video, Length 11:51 ABSTRACT: Certain medical devices fill crucial roles in health care, but their development is usually not straightforward.  For many devices, successful clinical introduction requires collaboration between academic research, industrial development, and funding sponsorship, sustained over many years.  Concepts that are first described in academic settings often encounter a unique set of difficulties in transit to industry and eventual public use. Some of the difficulties are related to university attitudes and policies, some to industrial culture and practices, and some to sponsor expectations.  Examples related to the development of implantable glucose sensors for use in diabetes will be discussed.
	Potential Advances in Biotech using Nanotech Materials and Processes Sungho Jin - Professor of Materials Science View Slides | Watch Video, Length 15:44 ABSTRACT: Biotechnology and nanotechnology are two of the most exciting and rapidly advancing technical fields. In recent years, there has been an increasing trend toward a convergence of these two fields for the benefit of biotechnology and eventual healthcare practices. Advances in some exciting nanoscale materials such as quantum dots, magnetic nanoparticles, nanowires and nanotubes allow exploration of new biotech device designs, more convenient and accurate imaging and diagnosis, and improved therapeutic processes. In this talk, some examples of potential applications of nanotechnologies for biotech fields such as bio-imaging, cancer treatment, drug delivery, DNA analysis, study of ion channels and related diseases, and modification of cell behavior, will be discussed.

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GRADUATE STUDENT POSTER WINNERS

Mechanical and Aerospace Engineering

Winner of the Research Expo Grand Prize Award, American Society of Mechanical Engineers (ASME) Best Poster, Department of Mechanical and Aerospace Engineering Best Poster
Poster Title: Changes in the Wall Shear Stresses During the Enlargement of Abdominal Aortic Aneurysms
Student: Anne-Virginie Salsac
Advisor: Professor Juan Lasheras

l-r ASME judge Nip Shah, Anne-Virginie Salsac, and MAE faculty judge prof. Serge Krasheninnikov

BIOCOM Best Poster
Poster Title: Engineered Transplantation Approaches of Adult Stem Cells for Degenerative Retinal Disorders
Student: Diana X. Yu
Advisor: Professor Gabriel Silva

BIOCOM judge Dr. Jackson Streeter (Photothera) and Diana X. Yu

Department of Bioengineering Best Poster [photo not available]
Poster Title: An Extracellular Matrix Microarray for Probing Cellular Differentiation
Student: Christopher J. Flaim
Advisor: Professors Sangeeta Bhatia and Shu Chien

Computer Science and Engineering

San Diego Software Industry Council Best Poster
Poster Title: Quantitative Spectral Decomposition for Stained Tissue Analysis
Students: Andrew Rabinovich and Sameer Agarwal
Advisor: Professor Serge Belongie

Andrew Rabinovich with SDSIC judges Anu Pathria and Walter Lee (both of Fair Isaac Corporation)

Department of Computer Science and Engineering Best Poster
Poster Title: Shotgun Protein Sequencing by Tandem Mass Spectra Assembly
Student: Nuno F. Bandeira
Advisor: Professor Pavel Pevzner

Nuno F. Bandeira and CSE faculty judge prof. David Kriegman

San Diego Telecom Council Best Poster and Department of Electrical and Computer Engineering Best Poster
Poster Title: Yellow-Red Light-Emitting Diodes Directly Grown on Gap Substrates
Student: Vladimir A. Odnoblyudov
Advisor: Professor Charles W. Tu

Vladimir A. Odnoblyudov and Telecom Council judge Franz Birkner (FXB Ventures)

Award for Excellence in the Use of Literature
Presented by the UCSD Science and Engineering Library
Poster Title: Multivariate Interpolation Decoding Beyond the Guruswami-Sudan Radius
Student: Farzad Parvaresh
Advisor: Professor Alexander Vardy

Poster judge Dawn Talbot and Farzad Parvaresh

Structural Engineering

Simon Wong Prize in Structural Engineering
Poster Title: Development of a Steel-Free Slab-on-Girder Modular FRP/Concrete Bridge System
Student: Lijuan (Dawn) Cheng
Advisor: Professor Vistasp Karbhari

Lijuan (Dawn) Cheng and poster judge Jack Savidge, von Liebig Center for Entrepreneurism & Technology Advancement at the Jacobs School.

Department of Structural Engineering Best Poster
Poster Title: Using Chaotic Interrogation and Attractor-Based Diagnostics for Structural Health Monitoring
Students: Timothy R. Fasel, Colin Olson, and Luke Overbey
Advisor: Professor Michael Todd

Timothy R. Fasel, Colin Olson, and Luke Overbey and structural engineering faculty judge prof. Scott Ashford

Award for Excellence in the Use of Literature
Presented by the UCSD Science and Engineering Library
Poster Title: Reinforced Thermoplastic Composites for Rehabilitation of Corrosion Damaged Steel Structures
Student: Corey T. Love
Advisor: Professor Vistasp Karbhari

Poster judge Dawn Talbot and Corey T. Love

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IMAGE GALLERY

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